Extended Data Fig. 4 in Bat coronaviruses related to SARS-CoV-2 and infectious for human cells
| Main Authors: | Temmam, Sarah, Vongphayloth, Khamsing, Baquero, Eduard, Munier, Sandie, Bonomi, Massimiliano, Regnault, Béatrice, Douangboubpha, Bounsavane, Karami, Yasaman, Chrétien, Delphine, Sanamxay, Daosavanh, Xayaphet, Vilakhan, Paphaphanh, Phetphoumin, Lacoste, Vincent, Somlor, Somphavanh, Lakeomany, Khaithong, Phommavanh, Nothasin, Pérot, Philippe, Dehan, Océane, Amara, Faustine, Donati, Flora, Bigot, Thomas, Nilges, Michael, Rey, Félix A., Werf, Sylvie van der, Brey, Paul T., Eloit, Marc |
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| Format: | info Image Journal |
| Terbitan: |
, 2022
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/6419077 |
Daftar Isi:
- Extended Data Fig. 4 | Analysisof thestability and conformational heterogeneityofRBD–hACE2 complexes. Timeseries (leftcolumn) and violinplots (rightcolumn) ofbackbone Root Mean Square Deviation (RMSD) fromtheinitial,energy-minimizedmodelcalculatedontheresiduesin RBD (A), hACE2 (B), attheinterface of RBDandhACE2 (C), andontheentirecomplex (D). Intheviolinplots,thewhitecirclecorrespondstothemedianvalue,the blackrectangleextendsfromthefirsttothethirdquantiles,andthethinblack linerepresentsthe 95% confidenceintervals.Populationof the 3 most significantclustersvisitedduringthecourseof the MDsimulations (E). Theanalysisisperformedfor 9 different MDsimulations:3 replicatesof the SARS-CoV-2 (shadesof green),BANAL-236 (shadesof red), and BANAL-52/103 (shadesofblue) RBD–hACE2 complexes.
- Published as part of Temmam, Sarah, Vongphayloth, Khamsing, Baquero, Eduard, Munier, Sandie, Bonomi, Massimiliano, Regnault, Béatrice, Douangboubpha, Bounsavane, Karami, Yasaman, Chrétien, Delphine, Sanamxay, Daosavanh, Xayaphet, Vilakhan, Paphaphanh, Phetphoumin, Lacoste, Vincent, Somlor, Somphavanh, Lakeomany, Khaithong, Phommavanh, Nothasin, Pérot, Philippe, Dehan, Océane, Amara, Faustine, Donati, Flora, Bigot, Thomas, Nilges, Michael, Rey, Félix A., Werf, Sylvie van der, Brey, Paul T. & Eloit, Marc, 2022, Bat coronaviruses related to SARS-CoV-2 and infectious for human cells, pp. 1-24 in Nature CLXVI on page 15, DOI: 10.1038/s41586-022-04532-4, http://zenodo.org/record/6419063