Studies in the Synthesis of Furocoumarins Part (XXIV) Synthesis of Difurocoumarin Derivatives
| Main Authors: | (MRS,) K. P. SANGHVI, K. N. TRIVBDI |
|---|---|
| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 1979
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/6364562 |
Daftar Isi:
- Chemistry Department, Faculty of Science, M. S. University of Baroda, Baroda 390 002 Manuscript received 2 September 1977, revised 4 July 1978, accepted 30 August 1978 4-Hydroxy-7-allyloxycoumarin(Ia), on allylation and Claisen rearrangement gave 7-allyioxy-2- methyl-2,3-dihydro-4-oxo-4H-furo(3,2-c)benzopyran(IIa) and 7-hydroxy-6- allyl-2-methyl-2,3-dihydro -4-oxo-4H-furo(3,2-c)benzopyran(IIb). (IIa), on further Claisen rearrangement gave (IIb) which on cyclisation followed by dehydrogenation afforded 2,7-dimethy1-4-oxo-4H-difuro(3,2-c : 2',3'-h) benzopyran(IV). 2,6,8-Trhuethy1- 4.oxo-4H-difuro(3,2-c : 3',2'-g)benzopyran(V) and 2,9-dimethyl -4-oxo-4H-difuro(3,2-c : 3',2'-benzopyran(VII) were similarly synthesised from 4-hydroxy-7-allyloxy 8-methylcoumarin(lc) and 4-hydroxy-6-allyloxycoumarin(Ie) respectively.