Synthesis of N-[3-(4-Aryl-l-piperazinyl)propy1]-4,4- bis(4-methoxyphenyl)piperidine-2,6-diones/ Tetrahydro- phthalimides/Camphorimides as Sedatives
| Main Authors: | U. V. KORGAONKAR, R. A. KULKARNI, S. D. SAMANT |
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| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 1983
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/6351070 |
Daftar Isi:
- Ramnarain Ruie College, Matunga, Bombay-400 019 University Department of Chemical Technology, Bombay-400 019 Manuscript received 16 September 1982, accepted 24 June 1983 N-[3-(4-Ary1-1-piperazinyl)propyl]- 4,4-bis( 4 - methoxyphenyl )piperidine - 2, 6 - diones (IX), camphorimides (XIII) and tetrahydrophthalimides (XI) were prepared by condensing 3-(4-aryl-1-piperazinyl)propylamine with 3,3-bis(4-methoxyphenyl)pentanedioic acid anhydride, camphoric acid anhydride and tetrahydrophthalic acid anhydride, respectively. IX were found to be inactive but XIII and XI exhibited significant sedative effect on mice.