Synthesis of Some N-[2-(2,4-Dialkoxy-5-Alkylphenyl) Ethyl]. 2,4-Dialkoxy-5-Alkylbenzenepropanamine Hydrochlorides as Antiamoebic Agents
| Main Authors: | P. L. KACHROO, RAJIVE GUPTA, S. R. DASS |
|---|---|
| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 1983
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/6348739 |
Daftar Isi:
- Department of Chemistry, University of Jammu, Jammu-180 001 Microbiology Section, Central Drug Research Institute, Lucknow-226 001 Manuscript received 8 March 1982, revised 5 November 1982, accepted la March 1983 Sixteen N-[2-(2,4-dialkoxy-5-alkylphenyl) ethyl]-2,4-dialkoxy-5-alkylbenzenepropanamine hydrochlorides have been synthesised from 2,4-dialkoxy-5-alkylbenzenepropanoyl chlorides by condensation with 2,4-dialkoxy-5-alkylbenzeneethanamines followed by LAH reduction. These have been tested in vitro against E. histolytica for antiamoebic activity.