Evaluation of antibiotic susceptibility pattern of bacterial Isolates from the Patients admitted in Intensive Care Units in a Tertiary Care Hospital
| Main Author: | Dr. Anshu Attri |
|---|---|
| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 2022
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/6342184 |
Daftar Isi:
- Abstract: Background: The present study attempts to know the antibiotic susceptibility pattern of bacterial Isolates from the Patients admitted in Intensive Care Units in a Tertiary Care Hospital. Material & Methods: The present study was conducted in the department of Microbiology Indira Gandhi Medical College and Hospital where in the clinical samples received from various ICUs were analysed for antibiotic susceptibility pattern. The duration of the study was from 14th January 2019 to 13th January 2020. Results: In the present study high rate of resistance was seen amongst the bacteria isolated. Escherichia coli had maximum sensitivity for meropenem (45.94%) and Klebsiella pneumoniae had maximum sensitivity for trimethoprim-sulfamethoxazole (23.18%) where as Klebsiella pneumoniae (96.38%) and Escherichia coli (91.90%) were found to be resistant to piperacillin. Non fermenter group of organisms showed maximum sensitivity for trimethoprim-sulfamethoxazole (32.18%) and maximum resistance to cefotaxime (94.26%), Pseudomonas aeruginosa had maximum sensitivity for piperacillin/tazobactam 40% and maximum resistance for aztreonam (97.78%), Acinetobacter baumannii had maximum sensitivity for trimethoprim-sulfamethaxole 12.24% and maximum resistance to quinolones and carbapenem group of drugs (97.96%). Staphylococcus aureus, coagulase negative Staphylococcus and Enterococcus were sensitive to linezolid. Staphylococcus aureus (97.45%) and coagulase negative Staphylococcus (95.46%) showed maximum resistance for ampicillin. Enterococcus spp. showed maximum resistance for tetracycline (90.91%). Multidrug resistant bacteria isolated were MRSA, ESBL, VRE, MDR Pseudomonas aeruginosa and PDR Acinetobacter baumannii. Conclusion: Early initiation of antimicrobial therapy based on antibiotic susceptibility pattern of different ICUs and influence the outcome of patients admitted to these ICUs.