4-Thiazolidinones as Potential Antibacterial and Antitubercular Agents
| Main Authors: | N. C. DESAI, H. K. SHUKLA, R. R. ASTIK, K. A. THAKER |
|---|---|
| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 1984
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/6330725 |
Daftar Isi:
- University Department of Chemistry, Bhavnagar University, Bhavnagar-364 002 Manuscript received 6 August 1982, revised 30 March 1984, accepted 17 June 1984 2-Aryl-3-[ 3-(4-methyl/methoxyphenyl)-thiazolldine-2,4-dione-5-yl]-4-thiazolidinones have been prepared from the reaction of thioglycolic acid with azomethines in dry benzene. The azomethines have been prepared by condensation of different aromatic aldehyde with 5-amino-3-(4- methyl/methoxyphenyl)-thiazolidine·2,4-dione. 4-Thiazolidinones show antibacterial activity when tested against S. aureus and E. coli by nutrient agar pour plate method, and have been tested against H27Rv strain of Mycobacterium tuberculosis.