Synthesis of Some New 5-Aryl/Aryloxymethyl-2-Chloro-1,3,4-0xadiazoles and their Oxadiazoloquinazolone Derivatives as Potential Pesticides
| Main Authors: | H. SINGH, L. D. S. YADAV, B.K. BHATTACHARYA |
|---|---|
| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 1984
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/6327424 |
Daftar Isi:
- Department of Chemistry, University of Gorakhpur, Gorakhpur-273 001 Tokyo Institute of Technology, Midori-Ku, Yokohama, 227, Japan K. U. L., Laboratorium Voor Organische Scheikunde, Celcstijnenlaan 200 F, B-3030, Heverlee, Belgium Manuscript received 2 December 1980, revised 19 October 1982, accepted 20 May 1983 Several 5-aryl/aryloxymethyl-2-chloro-1,3,4-oxadiazoles (III) have been prepared by treating 2-aryl/aryloxymethyl-\(\bigtriangleup\)2 -1,3,4-oxadizolin-5-ones (IIa) with POCI3 /PCl5. The latter were prepared by cyclisation of their corresponding N-aroyl/aryloxyacetylureas with NaOBr/NaOH. The 5-aryl/aryloxymethyl-2-chloro-1,3,4-oxadiazoles (III) have been condensed with anthranilic or substituted anthranilic acid to yield 2-aryl/aryloxy-methyl-1,3,4-oxadiazolo[2,3-b]quinazol-5-ones (IV). Eleven of these compounds have been screened and compared with 2, 4-D and Dithane M-45 for their berbicidal and fungicidal activities, respectively against two weeds Argemone mexicana and Cyperus rotundus, and two fungi Aspergillus niger and Helminthosporium oryzae. Based on the screening data a possible activity relationship has been given.