Some New 2-Aryl-3-isonicotamido-4-thiazolidinones and their 5-Carboxymethyl Homologues as Potential Antitubercular and Antibacterial Agent
| Main Authors: | N. C. DESAI, H. K. SHUKLA, K. A. THAKER |
|---|---|
| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 1984
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/6321848 |
Daftar Isi:
- Department of Chemistry, Bhavnagar University, Bhavnagar-864 002 Manuscript received 29 March 1983, accepted 27 February 1984 4-Thiazolidinones of the type (II) have been synthesised by condensing hydrazones of the type (I) with thioglycolic acid in benzene solution. Hydrazones have been prepared by condensing different aromatic aldehydes with isoniazide in ethanol (95%). Compounds (I) and (II) showed remarkable antibacterial and antitubercular activity against E. coli, S. aureus and Mycobacterium tuberculosis, strain H27Rv