Oxidation of α-Amino Acids with Sodium N-Bromo-p-Toluene Sulphonamide A Kinetic Study
| Main Authors: | D. S. MAHADEVAPPA, s. ANANDA, (late) M. B. MADE GOWDA, K. S. RANGAPPA |
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| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 1984
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/6320087 |
Daftar Isi:
- Department of Post-graduate Studies & Research in Chemistry, University of Mysore, Manasagangothri, Mysore-570 006 Manuscript received 16 June 1983, revised 19 November 1983, accepted 13 February 1984 Kinetic investigations of the oxidation of glycine, valine, alanine and leucine by-sodium N-bromo-p-toluenesulfonamide or bromamine-T (BAT) have been made in acetate buffer of \(\mathcal{p}\)H 6 (isoelectric \(\mathcal{p}\)H) at 35o. The rate shows a first order dependence on oxidant concentration but is fractional in [amino acid]. The influence of halide ions, ionic strength,\(\mathcal{p}\)-toluenesulfonamide and varying dielectric constant of medium on the rate has been studied. The formation constant (K1 ) and decomposition constant (k2 ) of the amino acid-BAT complex have been determined at different temperatures and linear free energy relations have been tested. The rate of oxidation increases in the order leucine > alanine > valine > glycine.