Synthesis of Some Substituted(3N- aminomethyl-1'-phenyl-4'-amino )substituted phenyl-4(3H)-quinazolones as Antiamoebic Agents
| Main Authors: | PRAMILLA SHAH, V. K. SAXENA, V. S. MISRA |
|---|---|
| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 1985
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/6319197 |
Daftar Isi:
- Department of Chemistry, Lucknow University, Lucknow-226 007 Manuscript received 3 August 1982, revised 7 May 1984, accepted 18 January 1985 Thirty two new substituted(3N-aminomethyl-1'-phenyl-4'-amido)substituted phenyl-4(3H)-quinazolones were synthesised and screened for in vitro amoebicidal activity against the axenic culture of Entamoeba histolytica. Some of these compounds have displayed significant amoebicidal activity at a concentration of 125 μg ml-1.