bowang-lab / OCAT (One Cell At a Time) A unified framework to integrate and analyze single-cell RNA-seq data
| Main Authors: | Wang, Chloe Xueqi, Zhang, Lin, Wang, Bo |
|---|---|
| Format: | info software Journal |
| Terbitan: |
, 2021
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/6270540 |
Daftar Isi:
- OCAT provides a fast and memory-efficient framework for analyzing and integrating large-scale scRNA-seq data. OCAT constructs sparse representation of cell features through ghost cells in the datasets. These ghost cells serve as bridges to inform on cell-cell similarity between the original cells. With the sparse features extracted, OCAT provides an efficient framework for cell type clustering and dataset integration that achieves state-of-the-art performance.