Fluorine containing Bioactive Heterocycles

Main Author: KRISHNA C. JOSHI
Format: Article Journal
Bahasa: eng
Terbitan: , 1986
Subjects:
Online Access: https://zenodo.org/record/6253363
Daftar Isi:
  • Department of Chemistry, University of Rajasthan, Jaipur-302 004 In recent decades, there has been considerable interest in medical applications and biochemistry of organic compounds containing fluorine. The discovery of 5-fluoronracil in the fifties is a classical example of a heterocyclic compound where the replacement of even one hydrogen by a fluorine atom led to great modification in biological activity of the parent non-fluorinated heterocycle. This presentation gives a background to this exciting new area in organic chemistry and briefly describes some of the recent work in the author's laboratory.