Fluorine containing Bioactive Heterocycles
Main Author: | KRISHNA C. JOSHI |
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Format: | Article Journal |
Bahasa: | eng |
Terbitan: |
, 1986
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Subjects: | |
Online Access: |
https://zenodo.org/record/6253363 |
Daftar Isi:
- Department of Chemistry, University of Rajasthan, Jaipur-302 004 In recent decades, there has been considerable interest in medical applications and biochemistry of organic compounds containing fluorine. The discovery of 5-fluoronracil in the fifties is a classical example of a heterocyclic compound where the replacement of even one hydrogen by a fluorine atom led to great modification in biological activity of the parent non-fluorinated heterocycle. This presentation gives a background to this exciting new area in organic chemistry and briefly describes some of the recent work in the author's laboratory.