Effect of some Organotin Halides, Pseudohalides and their Complexes on Oxidative Enzymes and CNS Activities

Main Authors: P. C. SRIVASTAVA, S. K. SRIVASTAVA, P. SINGH
Format: Article Journal
Bahasa: eng
Terbitan: , 1990
Subjects:
Online Access: https://zenodo.org/record/6244086
Daftar Isi:
  • Department of Chemistry, University of Lucknow, Lucknow·226 007 Manuscript received 21 September 1988, revised 30 April 1990, accepted 3 July 1990 Several di- and triphenyltin(IV) halides and pseudohalides have been screened for their gross CNS activity ( in vivo ) and for monoamine oxidase and pyruvate oxidase inhibitory activities ( in vitro) in rat The compounds were found to be CNS depressants. Ph2SnCI2 Ph2SnCI and Ph2 SnNCS have shown significant inhibition against both the tested enzymes.