Studies on Acetamide Derivatives. Part-II. Preparation, Antimicrobial and Anthelmintic Activity of N-Arylaminoacetylbenzimidazole/ sulphadiazine or sulphamethazine and N-Arylbenzimidazol-1-yl/sulphadiazin-4-yl or sulphamethazin-4-yl/ acetamides
| Main Authors: | V. H. SHAH, N. A. CHAUHAN, A. R. PARIKH |
|---|---|
| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 1987
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/6236615 |
Daftar Isi:
- Department of Chemistry, Saurashtra University, Rajkot 360 005 Manuscript received 24 June 1985, revised 14 July 1987, accepted 18 September 1987 We have synthesised N-arylaminoacetylbenzimidazole/sulphadiazine or sulphamethazine by the condensation of N-chloroacetylbenzimidazole or 4-N-chloroacetylsulphadiazine derivatives with different aromatic amines. N-Arylbenzimidazol-1- yl/sulphadiazin-4-yl- or sulphamethazine-4-yl-acetamides were also obtained by the condensation of benzimidazole or sulphadiazine derivatives with N-chloroacetylated arylamines. The products were screened for antimicrobial and anthelmintic activities. The constitution of the product was supported by ir spectra and elemental analysis.