Studies on Nitrofuran Heterocycles. Part-II. Synthesis and Antibacterial Activity of 2-Aryl-4-( 5-nitro-2-furyl)thiazoles

Main Authors: B. SIIIVARAMA BOLLA, BALAKRISHNA KALLURAYA, SARVOTTAM Y. A MBEKAR
Format: Article Journal
Bahasa: eng
Terbitan: , 1987
Subjects:
Online Access: https://zenodo.org/record/6200567
Daftar Isi:
  • Department of P. G. Studies and Researoh in Chemistry, Mangalore University, Mangalagangothri-574 199 Department of P. G. Studies and Research in Chemistry. University of Mysore, Manasagangothri-570 006 Manuscript received 22 September 1986, accepted 10 July 1987 The preparation of fourteen new 3-aryl-4-(5-nitro-2-furyl)thiazoles is described. These compounds are evaluated for antibacterial activity against both gram-positive and gram-negative bacteria. The results of the screening indicate that the title comĀ­pounds carrying o-chloro, o-bydroxy, p-nitro and dimethoxy substituents in the aryl moiety possess excellent antibacterial activity against all the organisms tested.