Studies on Thiazolidinones. Part-XXI. Synthesis of Thiazolidinone and their Derivatives from 4-[S-(Benzo- thiazoly1-2ʹ)mercaptoacetyl]thiosemicarbazides

Main Authors: M. SEN, N. MISHRA, A. NAYAK
Format: Article Journal
Bahasa: eng
Terbitan: , 1990
Subjects:
Online Access: https://zenodo.org/record/6164499
Daftar Isi:
  • Department of Chemistry, Sambalpur University, Jyoti Vihar, Burla-768 017 ManuscrIpt received 10 August 1989, revised 17 October 1989, accepted 21 November 1989 4-[S-(Benzothiazolyl-2')mercaptoacetyl]thiosemicarbazides (2 ; R=H and C4H5) were synthesised from 1[S-(benzothiazoly1-2ʹ)]mercaptomethylhydrazide (1) by react­ing with potassium thiocyanate and phenyl isothiocyanate respectively. The thiosemi­carbazides afforded thiazolidinones (4a and 5a) through different routes. The thia­zolidinones furnished arylidene derivatives (4b and 5b) with aromatic aldehydes and aminometbyl compounds (6) through Mannich reactions. The structure of the com­pounds are established using spectral and analytical data.