Synthesis and Antifungal Activity of some 1,4-Disubstituted-thiosemicarbazldes, 2,5-Disubstituted-1,3,4-thiadiazoles and 3,4-Disubstituted-5-mercapto-1,2,4-triazoles
| Main Authors: | R. K. MISHRA, R. K. TEWARI, SHISHIR K. SRIVASTAVA, S. C. BAHEL |
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| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 1991
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/6135317 |
Daftar Isi:
- Department of Chemistry, University of Gorakhpur, Gorakhpur-273 009 Manuscript received 6 March 1990, revised 22 November 1990, accepted 6 December 1990 THIOSEMICARBAZIDES possessing —N—C=S group, is an essential structural feature responsible for various biocidal1 properties. The acidic cyclisation of thiosemicarbazides leads to 1,3,4-thuiadiazoles, which also display various biological activities2,3. Various substituted-triazoles4 are also known to exhibit significant biological activities. Keeping these facts in view, the title compounds have been synthesised and some of them screened for their antifungal activity against two fungi, viz. Aspergillus niger and Hαminthosporium oryzαe.