Synthesis of some New Mannich Bases, Sulphides and Disulphides of 1,3,4-Oxadiazol-thiones as Potential Antifungal Agents
| Main Authors: | R. K. TEWARI, R. K. MISHRA, SHISHIR K. SRIVASTAVA, S. C. BAHEL |
|---|---|
| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 1991
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/6135048 |
Daftar Isi:
- Department of Chemistry, University of Gorakhpur, Gorakhpur-273 009 Manuscript received 27 March 1990, revised 14 November 1990, accepted 6 December 1990 VARIOUS 3, 5-disubstituted-1, 3,4-oxadiazol-2-thiones and several benzidine derivatives display biological activities1-2. Several oxadiazolyl sulphides and disulphides also exhibit biological activity3. In view of these observations the title compounds, viz. the sulphides, disulphides, benzidine and piperazine derivatives and Mannich bases of substituted-1,3,4- oxadiazoi-2-thiones have been prepared to evaluate their biological activities against two fungi, viz. Aspergillus niger and Helminthosporium oryzαe.