Reaction of Ethyl Chloroglyoxalate Arylhydrazone with Heterocyclic Amidine and Difunction Amino Derivatives
| Main Authors: | M. K. A. IBRAHIM, M. S. EL·GHARIB, A. M. FARAG, M. R. H. ELMOGHAYER |
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| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 1988
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/6035359 |
Daftar Isi:
- Chemistry Department, Faculty of Science, Cairo University, Giza, A. B. Egypt Manuscript received 10 November 1986, revised 9 November 1987, accepted 13 January 1988 The ethyl chloroglyoxalate p·tolylhydrazones (1) react with 5-amino-3-phenyl- pyrazole, 3-aminotriazole and 2-aminobenzimidazole in triethylamine solution to give the corresponding pyrazolo[4,5-c]pyrazole (9), triazolo[4,5-c]triazole (12) and benzimidazolylamidrazone derivatives (14), respectively. The reaction mechanism has been suggested as 1,3-dipolar cycloaddition of nitrileimine or alkylation reaction. Also the hydrazidoyl chlorides (1) react with o-phenylenediamine, o-aminophenol and anthranelic acid in DMF/triethylamine to give benzotriazine, benzoxazine and benzotriazipinone derivatives (18, 20 and 23), respectively. The structural assignment are based on elemental analysis and spectral data.