Efficient synthesis of novel imidazo[1,2-a]pyrimidine derivatives via one-pot three-component procedure

Main Authors: M.Heravi, Majid, Sadjadi, Samahe, Nahavandi, Fatemeh
Format: Article Journal
Terbitan: , 2015
Online Access: https://zenodo.org/record/5914532
Daftar Isi:
  • Synthesis of novel derivatives of imidazo[1,2-a]pyrimidine from one-pot three-component reaction of aldehydes, 2-amino-benzimidazole, and α-tetralone in the presence of catalytic amount of p-toluene sulfonic acid under reflux condition in EtOH has been presented. The simplicity and safety of the process, high yields and short reaction times were the main advantages of this protocol.