Spectrophotometric determination of Buclizine as hydrochloride (BUCZ) using 12/PMAP-SAc, AM/PTC and PMA/cobalt(II)/EDTA
| Main Authors: | V. Annapurna, G. Jyothi, V. Nagalakshmi, B. B. V. Sailaja |
|---|---|
| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 2009
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/5809957 |
Daftar Isi:
- Department of Chemistry, St. Theresa's College for Women, Eluru-534 003, Andhra Pradesh, India Department of Inorganic & Analytical Chemistry, Andhra University, Visakhapatnam-530 003, Andhra Pradesh, India E-mail : sailaja_bbv@yahoo.co.in Manuscript received 14 July 2008, accepted 24 December 2008 Simple, accurate and reproducible UV spectrophotometric methods were established for the assay of BUCZ based on the formation of precipitation, charge transfer and redox products. Precipitation/charge transfer complex formation of the BUCZ with 12/p-N-methyl amino phenol sulphate (PMAP)-sulphanilic acid (SAc) by Method A, the precipitation/complex formation with ammonium molybdate (AM)/potassium thiocyanate (PTC) by Method B and precipitation/redox reaction of BUCZ with phosphomolybdic acid (PMA)/CoII /EDTA by Method C were proposed. Determination of BUCZ in bulk form and in pharmaceutical formulations were also incorporated.