Microwave-induced cycloaddition of imines with acid chlorides in absence of a tertiary amine: Unprecedented synthesis of β-lactams in dimethylformamide
Main Authors: | Ram Naresh Yadav, Ashlee Chavez, Bimal Krishna Banik |
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Format: | Article Journal |
Bahasa: | eng |
Terbitan: |
, 2018
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Subjects: | |
Online Access: |
https://zenodo.org/record/5652672 |
Daftar Isi:
- Department of Chemistry, Faculty of Engineering & Technology, Veer Bahadur Singh Purvanchal University, Jaunpur-222 003, Uttar Pradesh, India Department of Chemistry, University of Texas-Pan American,1201 W. University Dr., Edinburg, TX 78539, USA The University of Texas M. D. Anderson Cancer Center, Department of Molecular Pathology, 1515 Holcombe Blvd, Houston, TX 77030, USA Current Address: Community Health System of South Texas, 3135 South Sugar Road, Edinburg, TX 78539, USA E-mail: bimalbanik10@gmail.com, bimal.banik@chsst.org Manuscript received 30 September 2018, accepted 01 November 2018 Synthesis β-lactams in N,N-dimethylformamide proceeds through cycloaddition of acid chlorides with imines in a domestic microwave oven in the absence of a tertiary base. This is an unprecedented observation.