Synthetic, spectral and biological activities of binuclear imidazolate-bridged complexes as Cu,Zn-SOD models possessing tris(2-aminoethyl)amine and amino acid derived ligands
| Main Authors: | M. Choudhary, S. P. Rawat, S. Bharti, Sangeeta, Noorusabah, K. Ahmad |
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| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 2016
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/5639315 |
Daftar Isi:
- Department of Chemistry, National Institute of Technology, Patna-800 005, Bihar, India E-mail : mukesh@nitp.ac.in Department of Chemistry, Govt. V. P.G. College, Maihar-485 771, Madhya Pradesh, India Manuscript received online 14 March 2016, accepted 10 August 2016 Synthetic, spectral and superoxide dismutase activities of the imidazolate-bridged binuclear copper(II)-zinc(II) complexes viz. [(L)Cu-Im-Zn(tren)]+ 1; [(L1)Cu-Im-Zn(tren)]+ 2; [(L2)Cu-Im-Zn(tren)]+ 3, derived from ( E)-2-(5-bromo- 2-hydroxybenzylideneamino)acetic acid (H2L); (S,E)-2-(5-bromo-2-hydroxybenzylideneamino)propanoic acid (H2L1); (R)- 2-(5-bromo-2-hydroxybenzylideneamino)-3-methylbutanoic acid (H2L2); tren = tris(2-aminoethyl)amine, Im = imidazolate ion, have been achieved. Magnetic moment values of hetero-binuclear complexes indicate that the imidazolate group can mediate antiferromagnetic interactions (S = 1/2) state. X-band EPR spectra of the complexes at different pH values in frozen solution showed that the metal complexes was stable in the pH range 6.50–11.00. Schiff base ligands (H2LH2L2) were synthesized by the condensation of equimolar (1 : 1) ratio of 5-bromosalicylaldehyde with glycine, alanine and valine, respectively, dissolved in ethanol. Biological (superoxide dismutase, antibacterial and antifungal) of these complexes have also been measured and compared with reported complexes.