Co-Infection of SARS-CoV-2 With Other Respiratory Viruses In Symptomatic Patients During Covid-19 Pandemic

Main Authors: ZAINI Adilahtul Bushro, ROSLI Nabila Farina, ABDUL AZIZ Nurul Izzati, ONN Muhammad Asyraf, MOHD ZIN Nabihah, ABD AZIZ Fatin Sarah, ZULKIPLI Nadia Soliha
Format: Proceeding poster Journal
Bahasa: eng
Terbitan: , 2021
Subjects:
Online Access: https://zenodo.org/record/5439507
Daftar Isi:
  • Introduction: Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) has become a global health problem. Co-infection of SARS-CoV-2 and other common respiratory viruses in symptomatic patients has been reported to be significantly common in the United States. To the best of our knowledge, there is no published evidence of SARS-CoV-2 co-infection reported in Malaysia. We performed a study on samples of patients with acute respiratory illnesses where the clinical symptoms are indistinguishable between both Coronavirus disease-19 (COVID-19) and other common respiratory virus infections to determine the extent of co-infections of SARS-CoV-2 with other common respiratory viruses. Methodology: Archived samples from patients with respiratory symptoms to Sungai Buloh Hospital from February 2020 to August 2020 were screened for COVID-19 using Allplex SARS-CoV-2 Assay as well as Allplex RV Essential Assay for detection of Influenza Virus (Flu A and B), Respiratory Syncytial Virus (RSV), Metapneumovirus (MPV), Adenovirus (AdV), Rhinovirus (HRV) and Parainfluenza Virus (PIV) using real-time PCR (RT-PCR). Results: A total of 354 samples were tested of which 32.2% (114/354) were positive for SARS-CoV-2 and 6.8% (24/354) were positive for HRV, AdV, MPV and RSV. The rate of SARS-CoV-2 co-infection with other common respiratory viruses was 2.2% (7/308), where the patients are all males aged between 4 to 27 years old with cough and fever as the common symptoms. HRV is the most common other respiratory virus infection which accounts for 71.4% (5/7) of co-infection with SARS-CoV-2. Conclusion: The rate of SARS-CoV-2 co-infection with other common respiratory viruses was quite low. However, SARS-CoV-2 infection during the COVID-19 pandemic could not rule out co-infection with other respiratory viruses. Disclaimer: Abstract text might vary slightly from what is displayed in the e-poster.
  • This poster was submitted to the 14th National Conference for Clinical Research (NCCR) in August 18-20, 2021. https://nccrconference.com.my/