Coordination compound, derivative of isothiosemicarbazide of transition metals as an inhibitor of superoxide radicals
| Main Authors: | Pantea Valeriana, Graur Vasilii, Andronache Lilia, Gulea Aurelian, Tsapkov Victor, Sardari Veronica, Gamaniuc Marina, Gudumac Valentin |
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| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 2021
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/5036805 |
Daftar Isi:
- A new biologically active coordination compound, which belongs to the class of transition metal isotiosemicarbazides - bis (2-acetate-o) -bis {[N-prop-2-en-1-yl-N'- (pyridin- 2-ylmethylidene) carbamo-hydrazonothioate] copper} dihydrate was obtained. It has established that this compound exhibits strong anti-radical properties to the action of the organic molecule with the superoxide radical. Due to this property, the obtained compound can have a wide application in medicine as an inhibitor of superoxide radicals in the human body, thus preventing damage to cells and tissues, atherosclerosis and carcinogenesis. The synthesized coordination compound expands the arsenal of superoxide radical inhibitors with high biological activity.