Data from: Algal toxin impairs sea lion memory and hippocampal connectivity, with implications for strandings
| Main Authors: | Cook, Peter F., Reichmuth, Colleen, Rouse, Andrew A., Libby, Laura A., Dennison, Sophie E., Carmichael, Owen T., Kruse-Elliott, Kris T., Bloom, Josh, Singh, Baljeet, Fravel, Vanessa A., Barbosa, Lorraine, Stuppino, Jim J., Van Bonn, William G., Gulland, Frances M. D., Ranganath, Charan |
|---|---|
| Format: | info dataset Journal |
| Terbitan: |
, 2016
|
| Subjects: | |
| Online Access: |
https://zenodo.org/record/5024085 |
Daftar Isi:
- Domoic acid (DA) is a naturally occurring neurotoxin known to harm marine animals. DA-producing algal blooms are increasing in size and frequency. Although chronic exposure is known to produce brain lesions, the influence of DA toxicosis on behavior in wild animals is unknown. We showed, in a large sample of wild sea lions, that spatial memory deficits are predicted by the extent of right dorsal hippocampal lesions related to natural exposure to DA and that exposure also disrupts hippocampal-thalamic brain networks. Because sea lions are dynamic foragers that rely on flexible navigation, impaired spatial memory may affect survival in the wild.
- Structural Scans Used For MorphometricsIncluded are T2-weighted structural scans in nifti format for each of the 41 sea lion subjects in this study. Scans are oblique, and were obtained perpendicular to the long axis of the hippocampus. These were the scans used in hippocampal morphometrics, using Quanta2 software, following tracing criteria detailed in the supplemental methods.Oblique_T2s.zipFunctional Connectivity MRI Data Part 1Included are the high-resolution structural scan used for defining thalamic ROIs, left and right thalamic ROIs in that space, and individual EPI and structural scans for two sea lion subjects. EPI data represents 15 minutes of continuous BOLD data under gas anesthesia. All scans are nifti format.fcMRI1.zipFunctional Connectivity MRI Data Part 2Individual EPI and structural scans for two sea lion subjects in nifti format. EPI data represents 15 minutes of continuous BOLD data under gas anesthesia.fcMRI2.zipFunctional Connectivity MRI Data Part 3Individual EPI and structural scans for two sea lion subjects in nifti format. EPI data represents 15 minutes of continuous BOLD data under gas anesthesia.fcMRI3.zipFunctional Connectivity MRI Data Part 4Individual EPI and structural scans for two sea lion subjects in nifti format. EPI data represents 15 minutes of continuous BOLD data under gas anesthesia.fcMRI4.zipFunctional Connectivity MRI Data Part 5Individual EPI and structural scans for two sea lion subjects, in nifti format. EPI data represents 15 minutes of continuous BOLD acquisition under gas anesthesia.fcMRI5.zipFunctional Connectivity MRI Data Part 6Individual EPI and structural scans for one sea lion subject, in nifti format. EPI data represents 15 minutes of continuous BOLD acquisition under gas anesthesia.fcMRI6.zip