EPIDERMOLYSIS BULLOSA ACQUISITA-LIKE CUTANEOUS REACTION REPORTED AFTER THE 2ND DOSE OF PFIZER-BIONTECH COVID-19 VACCINATION: A CASE REPORT
| Main Author: | Ahlam Al-Zahrani,MD, Bassam K Alhallani,MD, Ahmed Darwish,MD, Abdulrahman Al-Bahlool,MD, Abdullah Al-Badri,MD, Zeyad Helmy,MD |
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| Format: | Article Journal |
| Terbitan: |
, 2021
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| Online Access: |
https://zenodo.org/record/5014840 |
Daftar Isi:
- Although they are poorly investigated, cutaneous reactions to messenger RNA (mRNA)-based COVID-19 vaccinations have been documented. In this case report, we presented a case of cutaneous EBA-like response following the second shot of the Pfizer COVID vaccine in a 58-year-old woman with no previous chronic health conditions. The clinical picture showed skin rash with mild itching, burning sensation, and mild redness over her hands and face. On the 2nd day, large, tense blisters were developed. There were multiple eroded flaccid bullae with crusts; some were healed with hypopigmentation over the upper parts of the dorsal surface of the hands and feet. The histopathological report showed sub-epidermal cleft, re- epithelization, characteristic fibrinoid necrosis at the blister base, and no inflammatory cells. The patient's condition has improved on the administration of Prednisolone within eight weeks. Keywords: Epidermolysis Bullosa Acquisita; COVID-19, Vaccination, Pfizer BioNTech.