Data from: Specific MHC class I supertype associated with parasite infection and colour morph in a wild lizard population
| Main Authors: | Hacking, Jessica D., Stuart-Fox, Devi, Godfrey, Stephanie S., Gardner, Michael G. |
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| Format: | info dataset Journal |
| Terbitan: |
, 2019
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/4993849 |
Daftar Isi:
- The major histocompatibility complex (MHC) is a large gene family that plays a central role in the immune system of all jawed vertebrates. Non-avian reptiles are under-represented within the MHC literature and little is understood regarding the mechanisms maintaining MHC diversity in this vertebrate group. Here, we examined the relative roles of parasite-mediated selection and sexual selection in maintaining MHC class I diversity of a colour polymorphic lizard. We discovered evidence for parasite-mediated selection acting via rare-allele advantage or fluctuating selection as ectoparasite load was significantly lower in the presence of a specific MHC supertype (functional clustering of alleles); supertype four. Based on comparisons between ectoparasite prevalence and load, and assessment of the impact of ectoparasite load on host fitness, we suggest that supertype four confers quantitative resistance to ticks or an intracellular tick-borne parasite. We found no evidence for MHC-associated mating in terms of pair genetic distance, number of alleles or specific supertypes . An association was uncovered between supertype four and male throat colour morph. However, it is unlikely that male throat colouration acts as a signal of MHC genotype to conspecifics because we found no evidence to suggest that male throat colouration predicts male mating status. Overall, our results suggest that parasite-mediated selection plays a role in maintaining MHC diversity in this population via rare allele advantage and/or fluctuating selection. Further work is required to determine whether sexual selection also plays a role in maintaining MHC diversity in agamid lizards.
- Data for model set 1: Parasite-mediated selectionData used for model set 1 (parasite-mediated selection). See table S1 in associated article for further information.Data_ModelSet1_ParasiteMediatedSelection_Dryad.xlsxData for model set 2: MHC-associated matingData used for model set 2 (MHC-associated mating) and data used for Fisher's Exact test including mating status and MHC supertype presence. See table S1 in associated article for further information.Data_ModelSet2_MhcMateChoice_Dryad.xlsxData for model set 3: Signals of MHC genotypeData used for model set 3 (signals of MHC genotype) and Fisher's exact tests. See table S1 in associated article for further information.Data_ModelSet3_SignalsMhcGenotype_Dryad.xlsxHeterozygosity and relatedness dataData use to test for correlations between MHC variables and heterozygosity and relatedness. See associated article for further details.Data_HeterozygosityRelatedness_Dryad.xlsx