Study on rapid screening technology of antisense oligonucleotides for SARS-CoV-2

Main Author: SHEN,Huawei
Format: info publication-preprint Journal
Bahasa: eng
Terbitan: , 2021
Subjects:
Online Access: https://zenodo.org/record/4741538
Daftar Isi:
  • According to the structural characteristics of SARS-CoV-2 nucleic acid,SARS-CoV-2 genomes were virtually segmented.After comparing with human genome,44707 SARS-CoV-2 genomes and 26 primates' genomes, 18 antisense oligonucleotides sequences were selected.Experimental results show that the combined inhibitory effect reaches 100% .