A COMPARATIVE STUDY OF INJ. KETOROLAC ALONG WITH INFILTRATION OF INJ. BUPIVACAINE AT OPERATION SITE & INJ. KETOROLAC ALONG WITH INTRA-PERITONEAL INFILTRATION OF INJ. BUPIVACAINE FOR PAIN RELIEF AFTER POST LAPAROSCOPIC CHOLECYSTECTOMY
| Main Author: | Dr Maham Shahbaz , Dr Rabeea Sattar, Dr Hina Khan |
|---|---|
| Format: | Article Journal |
| Terbitan: |
, 2021
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| Online Access: |
https://zenodo.org/record/4413773 |
Daftar Isi:
- Aim: To study the analgesic effect of injection Ketorolac along with Intra-incisional infiltration of injection Bupivacaine & compare it with the analgesic effect of injection Ketorolac along with Intra-peritoneal infiltration of injection Bupivacaine. Place and Duration: At the Surgical Unit-II and Anesthesia Unit-I of Sir Ganga Ram Hospital, Lahore for one-year duration from June 2019 to June 2020. Patients and Methods: This was a prospective, randomized, double-blind study in 120 patients undergoing laparoscopic (LC) cholecystectomy, divided into 2 groups of 60 patients each. Group B received a 30 ml intraperitoneal injection of 0.25% bupivacaine along with an injection of Ketorolac 30 mg intravenously, and group A received a 30 mg injection of Ketorolac intravenously along with a local infiltration injection of 0.25% bupivacaine, 5 ml each in all 4 ports at the end of surgery. Postoperative; the investigator, who was unaware of the procedure, rated the pain with a visual analog scale (VAS) at 1, 6, 12 and 24 hours after surgery. Injection Nalbuphine 5 mg was administered intravenously as rescue pain reliever at the patient's request during the first 24 hours. Results: The VAS results of the 2 groups show that group B has less results compared to group A, although it was statistically insignificant (p> 0.05). Also, the need for emergency analgesic treatment was significantly lower in group B compared to group A (p <0.00). Conclusion: At the end of the study, we concluded that the intraperitoneal infiltration of bupivacaine together with the injection of Ketorolac is more effective in reducing pain after LC. Key words: Ketorolac injection, laparoscopic pain after cholecystectomy, intraperitoneal and operative Bupivacaine infusion