The influence of natural mineral water on the structural and functional changes in the rat kidneys under urolithiasis modelling
| Main Authors: | Kucherenko, Mykola, Nasibullin, Boris, Gushcha, Sergey, Bobro, Elena, Badiuk, Nataliia, Glushchenko, Victoria, Kholodnitskiy, Igor, Oslavskaya, Tatyana |
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| Format: | Article Journal |
| Terbitan: |
, 2020
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| Online Access: |
https://zenodo.org/record/4323386 |
Daftar Isi:
- Kucherenko Mykola, Nasibullin Boris, Gushcha Sergey, Bobro Elena, Badiuk Nataliia, Glushchenko Victoria, Kholodnitskiy Igor, Oslavskaya Tatyana. The influence of natural mineral water on the structural and functional changes in the rat kidneys under urolithiasis modeling. Balneo Research Journal. DOI: http://dx.doi.org/10.12680/balneo.2020.382 Vol.11, No.4, December 2020. p: 477–480 https://zenodo.org/deposit/4323386 The influence of natural mineral water on the structural and functional changes in the rat kidneys under urolithiasis modeling Kucherenko Mykola1, Nasibullin Boris2, Gushcha Sergey2, Bobro Elena2, Badiuk Nataliia3, Glushchenko Victoria1, Kholodnitskiy Igor1, Oslavskaya Tatyana1 1State Institution “South Ukrainian National Pedagogical University named after K. D. Ushynsky”, Odesa, Ukraine; 2State Institution «Ukrainian Research Institute of Medical Rehabilitation and Resort Therapy of Ministry of Health of Ukraine», Odesa, Ukraine; 3State Enterprise "Ukrainian Research Institute of Transport Medicine of the Ministry of Health of Ukraine", Odessa Abstract In the experiment on the white Wistar rats, the authors evaluated kidneys changes in urolithiasis modelling (Kidney stone disease, KSD) and the possibility of correcting these changes by internal use of the mineral water (MW) with high organic matter content. The results of the studies revealed structural pathological changes in the kidneys in the form of changes of the part of glomeruli capillaries and gross changes in the kidneys tubules and interstitial layers. At the same time, the functional kidneys activity is manifested in the form of increased urination and a significant increase in urination. Urine metabolic characteristics are also change. The use of MW leads to an improvement in the capillaries of the renal corpuscles structure and almost complete restoration of the tubules structure. The functional activity of the kidneys and the quality of urine have significantly improving. The authors believe that the organic compounds of MW, which mainly determine its biological activity, contribute to the improvement of the regulation of metabolic processes and, accordingly, have a positive effect on the structural and functional parameters of the kidneys.. Keywords: urolithiasis; structural and functional characteristics of the kidneys; mineral water