Leishmaniasis: features of the clinical course
| Main Authors: | V.N. Kosinets, A.A. Savushkina, Gamara Mohamed Ali, N.V. Batkaeva, M.A. Bobrov, E.A. Batkaev |
|---|---|
| Format: | Article Journal |
| Bahasa: | rus |
| Terbitan: |
, 2020
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| Online Access: |
https://zenodo.org/record/4290834 |
Daftar Isi:
- Relevance. Leishmaniasis, a protozoal infection transmitted by mosquito bites, causes a wide range of manifestations of the disease from skin forms to severe visceral lesions. It is estimated that 1.3 million new cases of leishmaniasis occur worldwide each year, mostly in countries with tropical climates. According to the World Health Organization (WHO) (2017), leishmaniasis ranks second after malaria as the cause of death from tropical diseases, with 20,000 to 30,000 deaths annually. There are visceral and cutaneous leishmaniasis. Cutaneous leishmaniasis is most often observed. It is considered that leishmaniasis should be suspected in any person living in / visiting epidemic dangerous countries, since in the case of visceral leishmaniasis, a late diagnosis can be the cause of the patient’s death. Materials and methods. We describe an observed clinical case of leishmaniasis in a patient who was 14 months ago in a country with a tropical climate, where he was bitten by mosquitoes. 6 months after the «mosquito attack», dense nodules appeared on the skin in the area of the left wrist joint, and the subfebrile temperature remained. He was examined by local doctors and diagnosed with leishmaniasis. After treatment with Glucantim, a course of 6 injections, the rash was resolved. However, after 2 months, the disease recurred. Results. In our clinic the diagnosis was confirmed: Cutaneous ieishmaniasis. The performed therapy: cryodestruction of tubercle elements against the background of Delagil 0.25 3 times a day for 10 days, Sulfadimetoxin 0.5 1 time for 10 days and later – Itraconazole 100 mg 2 times a day for 4 weeks allowed to achieve clinical recovery. Conclusion. Caution about possible protozoal parasitic infection – Leishmaniasis in people who have lived and/or visited countries with tropical climates and have skin rashes should be very high. Timely diagnosis and treatment prevents serious complications. Key words: visceral and cutaneous leishmaniasis, clinical case of leishmaniasis, therapy