ВЛИЯНИЕ ЯНТАРНОЙ КИСЛОТЫ НА СОСТОЯНИЕ ЗУБОЧЕЛЮСТНОЙ СИСТЕМЫ И ТКАНЕВОЙ ПОЛОСТИ РТА КРЫС ПРИ ДЕЙСТВИИ ВНУТРИУТРОБНОЙ ГИПОКСИИ И КАРИЕСОГЕННОГО РАЦИОНА = INFLUENCE OF SUCCINIC ACID ON THE CONDITION OF THE DENTITION AND TISSUE CAVITY OF THE MOUTH OF RATS UNDER THE ACTION OF INTRAUTERINE HYPOXIA AND CARIOGENIC DIET
| Main Authors: | Ivanov, V. S., Schneider, S. A., Tkachenko, E. K. |
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| Format: | Article Journal |
| Terbitan: |
, 2020
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| Online Access: |
https://zenodo.org/record/4118664 |
Daftar Isi:
- Ivanov V. S., Schneider S. A., Tkachenko E. K. INFLUENCE OF SUCCINIC ACID ON THE CONDITION OF THE DENTITION AND TISSUE CAVITY OF THE MOUTH OF RATS UNDER THE ACTION OF INTRAUTERINE HYPOXIA AND CARIOGENIC DIET. ВІСНИК МОРСЬКОЇ МЕДИЦИНИ. 2020;3(88): 71-77. ISSN 0049-6804. DOI http://dx.doi.org/10.5281/zenodo.4118664 http://www.herald.com.ua УДК 616.314+616.716.8:611.08 DOI http://dx.doi.org/10.5281/zenodo.4118664 ВЛИЯНИЕ ЯНТАРНОЙ КИСЛОТЫ НА СОСТОЯНИЕ ЗУБОЧЕЛЮСТНОЙ СИСТЕМЫ И ТКАНЕВОЙ ПОЛОСТИ РТА КРЫС ПРИ ДЕЙСТВИИ ВНУТРИУТРОБНОЙ ГИПОКСИИ И КАРИЕСОГЕННОГО РАЦИОНА В. С. Иванов, С. А. Шнайдер, Е. К. Ткаченко INFLUENCE OF SUCCINIC ACID ON THE CONDITION OF THE DENTITION AND TISSUE CAVITY OF THE MOUTH OF RATS UNDER THE ACTION OF INTRAUTERINE HYPOXIA AND CARIOGENIC DIET Ivanov V. S., Schneider S. A., Tkachenko E. K. State Institution "Institute of Dentistry and Maxillofacial Surgery of the National Academy of Medical Sciences of Ukraine" vestnik@ukr.net Summary The aim: to study the influence of the dietary supplement "Succinic acid" on the condition of the dentition and tissues of the oral cavity of rats under conditions of intrauterine hypoxia and cariogenic diet. Materials and methods. The experiment was carried out on 47 white Wistar rats of herd breeding. In females, from 10 to 19 days of gestation, tissue hypoxia was reproduced by intraperitoneal administration of sodium nitrite (NaNO2) at a dose of 10 mg / kg of body weight to rats. During 30 days, the rats received a solution of the dietary supplement "Succinic acid" per os against the background of the experimental effects (hypoxia + cariogenic diet). Research results. Succinic acid, administered orally to the offspring of rats that underwent intrauterine hypoxia, showed antioxidant, anti-inflammatory properties Key words: tissue intrauterine hypoxia, cariogenic diet, succinic acid, antihypoxic effects, rats.