A Facile and Effective Four-Component Synthesis of Benzo[4,5]imidazo[1,2-a]-pyrimidine-3-carboxamides Based on Diketene
| Main Authors: | M Heravi; Majid, Ghanbarian, M., Beheshtiha, S.Y.S. |
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| Format: | Article Journal |
| Terbitan: |
, 2019
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/4050459 |
Daftar Isi:
- A novel and efficient four component reaction involving diketene, primary amines, aromatic aldehydes and 2-amino-benzimidazole in the presence of I2 in refluxing EtOAc for the synthesis of benzo[4,5]imidazo[1,2-a]-pyrimidine-3-carboxamides is reported. Good yields, mild reaction conditions and facile isolation of products in pure forms are advantageous of this methodology.