ToxicoDB: an integrated database to mine and visualize large-scale toxicogenomic datasets
| Main Authors: | Kadambat Nair, Sisira, Eeles, Christopher, Ho, Chantal, Beri, Gangesh, Yoo, Esther, Tkachuk, Denis, Tang, Amy, Nijrabi, Parwaiz, Smirnov, Petr, GJ Jennen, Danyel, Haibe-Kains, Benjamin |
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| Format: | info dataset Journal |
| Terbitan: |
, 2020
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/4024991 |
Daftar Isi:
- This page links to the data associated with the publication "ToxicoDB: an integrated database to mine and visualize large-scale toxicogenomic datasets ". The data have been curated and analyzed using our open-source R package, ToxicoGx (https://github.com/bhklab/ToxicoGx) and are available publicly in the ToxicoDB web application (www.toxicodb.ca). Please see the included DOIs below, or download the .csv file which contains the names, dates and DOIs of all datasets listed here. The TGGATES data was generated by Igarashi Y, Nakatsu N, Yamashita T, Ono A, Ohno Y, Urushidani T, Yamada H. Open TG-GATEs: a large-scale toxicogenomics database. Nucleic Acids Res [Internet]. 2015 Jan;43(Database issue):D921–7. Available from: http://dx.doi.org/10.1093/nar/gku955 PMCID: PMC4384023. Data: TGGATEs humanldh (https://doi.org/10.5281/zenodo.3762812) TGGATEs humandna (https://doi.org/10.5281/zenodo.4024859) TGGATEs ratldh (https://doi.org/10.5281/zenodo.3762817) TGGATEs ratdna (https://doi.org/10.5281/zenodo.4024918) This Drug Matrix data was generated by Ganter B, Snyder RD, Halbert DN, Lee MD. Toxicogenomics in drug discovery and development: mechanistic analysis of compound/class-dependent effects using the DrugMatrix database. Pharmacogenomics [Internet]. 2006 Oct;7(7):1025–1044. Available from: http://dx.doi.org/10.2217/14622416.7.7.1025 PMID: 17054413. Data: Drug Matrix (https://doi.org/10.5281/zenodo.3766569)
- - This file has been updated to point to two new Tsets that are DNA viability counterparts of TG-GATEs dataset. - This file has been updated to point to the new versions of TGGATES_ratldh, TGGATES_humanldh and drugMatrix_rat - These tSets are now available using the downloadTSet function in the ToxicoGx pacakge; please see included documentation for usage instructions - This data is idententical to the last release but has updapted tSet DOIs and an appropriate version bump