The transcriptomic response of murine thyroid to iodide overload and the role of the Nrf2 antioxidant system
| Main Author: | Sykiotis, Gerasimos |
|---|---|
| Format: | info dataset |
| Terbitan: |
, 2020
|
| Subjects: | |
| Online Access: |
https://zenodo.org/record/4005814 |
Daftar Isi:
- Wild-type and Nrf2(Nfe2l2) knockout male C57BL6J mice 3-4 months old were administred 0.05% NaI in their drinking water for 7 days. Control mice were administered regular drinking water. After this treatment mice were euthanized and thyroids were excised for RNA preparation and then for mRNA and miRNA RNAseq. The file titled "metadata RNAseq mRNA thyroid" contains the experimental information as well as the allocation of sample numbers to the relevant groups. Briefly, 806 Knockout Iodide 829 Wild type Iodide 815 Knockout Control 811 Knockout Control 801 Knockout Iodide 836 Wild type Control 838 Wild type Control 807 Knockout Iodide 834 Wild type Control 827 Wild type Iodide 831 Wild type Iodide 804 Knockout Iodide 825 Wild type Iodide 841 Wild type Control 812 Knockout Control 803 Knockout Iodide 810 Knockout Control The fastq data have been uploaded. The ones with "miRNA" in their file name refer to miRNA sequencing. All the others refer to mRNA sequencing.