Gut microbiota and its impact on neuropsychiatric disorders
| Main Authors: | Wójcik, Magdalena, Dąbrowska, Justyna, Boreński, Grzegorz, Bator, Damian, Milanowska, Joanna |
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| Format: | Article |
| Terbitan: |
, 2020
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| Online Access: |
https://zenodo.org/record/3992560 |
Daftar Isi:
- Wójcik Magdalena, Dąbrowska Justyna, Boreński Grzegorz, Bator Damian, Milanowska Joanna. Gut microbiota and its impact on neuropsychiatric disorders. Journal of Education, Health and Sport. 2020;10(8):276‐285. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2020.10.08.032 https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/JEHS.2020.10.08.032 https://zenodo.org/record/3992560 The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019. © The Authors 2020; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 01.08.2020. Revised: 05.08.2020. Accepted: 20.08.2020. Gut microbiota and its impact on neuropsychiatric disorders Magdalena Wójcik1*, Justyna Dąbrowska1, Grzegorz Boreński1, Damian Bator1, Joanna Milanowska2 1Student Science Club at the Department of Applied Psychology, Medical University of Lublin, Lublin, Poland 2Department of Applied Psychology, Medical University of Lublin, Lublin, Poland *E-mail address: magdalena.wojcik967@gmail.com ORCID ID: Magdalena Wójcik https://orcid.org/0000-0002-0999-6284 Justyna Dąbrowska https://orcid.org/0000-0002-1356-6965 Damian Bator https://orcid.org/0000-0002-8464-932X Joanna Milanowska https://orcid.org/0000-0001-9741-1583 ABSTRACT Introduction: Over the last few decades, the interest of microbiota- gut – brain axis has increased. It is thought to have an impact on the overall health of the host. Gut microbiota and central nervous system can communicate in different ways. The connection between them is especially interesting in case of neuropsychiatric diseases The aim of the study: The purpose of this systemic review was to collect and analyse current data of the association between gut microbiota and neuropsychiatric disorders, specifically schizophrenia and bipolar disorder Material and method: Standard criteria were used to review the literature data. The search of articles in the PubMed and Google Scholar database was carried out using the following keywords: gut microbiota, dysbiosis, schizophrenia, bipolar disorder Description of the state of knowledge: Dysregulation of microbiota is a potential factor in pathogenesis of brain disorders. Gut microbiome is thought to be an important part of not only normal brain development, but also modulation of host physiological systems. Studies show that the composition of microbiota in psychiatric diseases including schizophrenia and bipolar disorder differs from healthy individuals. Many environmental factors can change the composition of microbiota and therefore potentially contribute to the development of many disorders, including neuropsychiatric disorders. Summary: Microbiota is a potential factor contributing to the onset or modulating the course of many illnesses, including brain disorders The subject of imbalanced microbiota composition give hope for finding etiology or improving treatment of many disorders. However, it still requires more studies. Key words: gut microbiota, dysbiosis, schizophrenia, bipolar disorder