ToxicoDB: an integrated database to mine and visualize large-scale toxicogenomic datasets (TGGATEs rat dataset)

Main Authors: Kadambat Nair, Sisira, Eeles, Christopher, Ho, Chantal, Beri, Gangesh, Yoo, Esther, Tkachuk, Denis, Tang, Amy, Nijrabi, Parwaiz, Smirnov, Petr, Seo, Heewon, GJ Jennen, Danyel, Haibe-Kains, Benjamin
Format: info dataset
Terbitan: , 2020
Subjects:
Online Access: https://zenodo.org/record/3762817
Daftar Isi:
  • This data was generated by Igarashi Y, Nakatsu N, Yamashita T, Ono A, Ohno Y, Urushidani T, Yamada H. Open TG-GATEs: a large-scale toxicogenomics database. Nucleic Acids Res [Internet]. 2015 Jan;43(Database issue):D921–7. Available from: http://dx.doi.org/10.1093/nar/gku955 PMCID: PMC4384023. The data have been curated and analyzed using our open-source R package, ToxicoGx (https://bioconductor.org/packages/devel/bioc/html/ToxicoGx.html) and are available publicly in the ToxicoDB web application (www.toxicodb.ca).
  • - This TSet includes the LDH counterpart viability measurements of rat data. - Converted the dataset structure to match the updated version of ToxicoGx currently being submitted to Bioconductor - Updated drug annotations in the dataset to use up to date cids, smiles, and inchikeys - The package can be accessed via Bioconductor : https://bioconductor.org/packages/devel/bioc/html/ToxicoGx.html OR run `devtools::install_github("bhklab/ToxicoGx")` in your R terminal