epiCaPture, A Urine DNA Methylation Test for the Early Detection of Aggressive Prostate Cancer
| Main Authors: | Cosgrave, Joanne, Conor, Adele, Jordan, Asia, Winrow, Deirdre, Perry, Antoinette |
|---|---|
| Format: | info software |
| Bahasa: | eng |
| Terbitan: |
, 2020
|
| Subjects: | |
| Online Access: |
https://zenodo.org/record/3749752 |
Daftar Isi:
- epiCaPture is a urine DNA methylation test for the early diagnosis of aggressive prostate cancer (PCa). The test is a non-invasive liquid biopsy test that investigates aberrant DNA methylation within a panel of 6 genes. This study primarily examined the importance of a digital rectal exam within the epiCaPture test. Additionally, it investigates the relationship between the amount of DNA within the patient sample and the detected levels of the housekeeper gene beta-actin. The study was carried out over six months as a final year research project with the School of Biology and Environmental Science within University College Dublin.