EVALUATION OF GENETIC MARKERS OF BONE METABOLISM IN PATIENTS WITH MAXILLOFACIAL ANOMALIESON THE BACKGROUND OF METABOLIC SYNDROME
| Main Authors: | Denga, А. Е., Verbitskaya, T. G., Rozhko, P. D. |
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| Format: | Article Journal |
| Terbitan: |
, 2020
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| Online Access: |
https://zenodo.org/record/3744363 |
Daftar Isi:
- Denga А. Е., Verbitskaya T. G., Rozhko P. D. EVALUATION OF GENETIC MARKERS OF BONE METABOLISM IN PATIENTS WITH MAXILLOFACIAL ANOMALIESON THE BACKGROUND OF METABOLIC SYNDROME. Актуальні проблеми транспортної медицини / Actual problems of transport medicine / 2020;1(59):59-64. ISSN 1818-9385 DOI http://dx.doi.org/10.5281/zenodo.3744363 http://aptm.org.ua EVALUATION OF GENETIC MARKERS OF BONE METABOLISM IN PATIENTS WITH MAXILLOFACIAL ANOMALIESON THE BACKGROUND OF METABOLIC SYNDROME 1Denga А. Е.,1Verbitskaya T. G.,2Rozhko P. D. 1State Institution «The Institute of Stomatology and Maxillo-facial Surgery NAMS of Ukraine» 2Odessa National Medical University Abstract Work shows that creation of dentofacial anomalies treatment plan and development of therapeutic and preventive measures to support orthodontic treatment in patients with metabolic syndrome and chronic generalized periodontitis, it is first necessary to take into account the status of osteogenesis markers Col1A1 and VDR to predict complications, occurrence and progression of periodontal tissue diseases, endothelial factor VEGF, antioxidant protection factor PON, as well as APOE lipoprotein metabolism markers, TGF osteoblast proliferation and a marker of bone tissue response to NOS loading. Key words: genetic markers; bone metabolism; orthodontic treatment; metabolic syndrome.