Formulation and Evaluation of Ondansetron HCL Mouth Dissolving Tablet
| Main Authors: | D.G. Umalkar, Gajanan P. Awate, S. J. Bidkar, G.Y. Dama |
|---|---|
| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 2020
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/3629106 |
Daftar Isi:
- Recent development in mouth dissolving tablet of Ondansetron hydrochloride were designed with a view to enhance patient compliance, reduce manufacturing cost and manufacturing time by using co-processed excipient i.e. DiCOM DC MD with direct compression method. Prepared Batches of tablet were evaluated for hardness, friability, drug content uniformity, wetting time, water absorption ratio and in vitro dissolution time. Based on in vitro time, prepare formulation were tested for in vitro drug release pattern (in pH7.4phosphate buffer).