The role of prooxidative and antioxidant processes in periodontal tissue in the mechanisms of formation of adrenalin damage of myocardium and experimental periodontitis and their correction with Corvitin
| Main Author: | Horodetskyy, Oleh |
|---|---|
| Format: | Article |
| Terbitan: |
, 2019
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| Online Access: |
https://zenodo.org/record/3575783 |
Daftar Isi:
- Horodetskyy Oleh. The role of prooxidative and antioxidant processes in periodontal tissue in the mechanisms of formation of adrenalin damage of myocardium and experimental periodontitis and their correction with Corvitin. Journal of Education, Health and Sport. 2019;9(11):269-276. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2019.09.11.024 https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/JEHS.2019.09.11.024 http://dx.doi.org/10.5281/zenodo.3575783 The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019. © The Authors 2019; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 06.11.2019. Revised: 14.11.2019. Accepted: 29.11.2019. UDК 616.314.18-002.4-092:612.015.11:616.127-085.224]-092.9 The role of prooxidative and antioxidant processes in periodontal tissue in the mechanisms of formation of adrenalin damage of myocardium and experimental periodontitis and their correction with Corvitin Oleh Horodetskyy1 1Danylo Halytsky Lviv National Medical University, Lviv, Ukraine Correspondence to:Oleh Horodetskyy, PhD student, Danylo Halytsky Lviv National Medical University, e-mail:oleh@profident-plus.lviv.ua Abstract The aim of our study was to determine the antioxidant activity and prooxidative processes in the formation mechanisms in periodontal adrenalin myocardial damage and experimental periodontitis and their correction with corvitin. For this purpose, we conducted a study on 54 nonlinear white male rats, which were divided into six groups. First - control, second, third, fourth and fifth - a group of animals with adrenaline injury of myocarditis during the course of experimental periodontitis before correction of corvitin to according to the 1st, 7th, 10th and 17th days of the experiment and the sixth group - animals with adrenaline injury of myocarditis during the course of experimental periodontitis after adjustment corvitin. The results showed that when combined pathology antioxidant activity of prooxidative processes going towards depression of antioxidant protection against the growing LPO. After entering corvitin - reduced rates of LPO and increases the activity of enzymes AOC, that indicating the antioxidant and cardioprotective properties of the drug. Keywords: adrenaline damage of myocarditis; experimental periodontitis; corvitin.