Investigation of the Relationship of the Shape and Size of Glycoprotein and It Function
| Main Authors: | Dr. Abdullah Sethar, Dr.Naimatuallah Leghari, Dr.Muhammad Ali Bhatti, Dr.Faiz Muhammad Shaikh |
|---|---|
| Format: | Article |
| Bahasa: | eng |
| Terbitan: |
, 2016
|
| Subjects: | |
| Online Access: |
https://zenodo.org/record/3531370 |
Daftar Isi:
- The resaerch investigates the Investigation of the relationship of the shape and size of glycoprotein and it function. It was found from this test that fullness was not related particle size or the amount of GP but empty particles are more elliptical than normal or dense particles. So RNA or NP only explain some of the variability in virus shape, but not the relationship between shape and size. Since RNA and NP density does not change during fusion activation, RNA and NP are not good explanation for the sudden change in shape. Dense particles are round, Some empty particles are elliptical but fullness does not change with fusion activation. It was further revealed that The correlation coefficient for LCMV, TCRV and PICV were all below the level that would be considered statistically meaningful or should small contradictory effects (Table 4.1) Most virions were covered with GPs but a few did not appear to have any. From this data it was concluded that GP density does not affect virus shape.