Ovarian Non-Hodgkin's Lymphoma from a Regional Cancer Centre in South India
| Main Authors: | Babu, Suresh, Amirtham, Usha, K.N, Lokesh, Babu.K, Govind, K.C, Lakshmaiah, Dasappa, Lokanatha, Premalata, C.S., Abraham Jacob, Linu, AH, Rudresh, LK, Rajeev, Arroju, Venugopal |
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| Format: | Article |
| Bahasa: | eng |
| Terbitan: |
, 2016
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| Online Access: |
https://zenodo.org/record/3349191 |
Daftar Isi:
- Primary Non-Hodgkin's Lymphoma of Ovary is a rare cancer. There is limited data in Indian population. Hence we undertook this retrospective observational study at our center in Southern India. This study includes 5 consecutive cases diagnosed as Primary Non-Hodgkin's Lymphoma of Ovary between January 2009 and December 2015. Primary Non-Hodgkin's lymphoma (NHL) of the ovary is rare with an incidence in the literature of 0.5% of NHL and 1.5% of ovarian tumours. Diffuse large B-cell type accounts for about 20% of PONHL. We studied five cases of primary ovarian NHL. All cases were diffuse large B-cell lymphoma of ovary. The patients ranged in age from 41years to 59 years with median age of presentation 50 years. Pain abdomen was the most common symptom (3/5-60%). According to Ann Arbor stage- Advanced stage ( IVE) was seen in 3 patients ( 60 %) and the rest 2 patients (40% ) had stage IE. 4 patients had Eastern co-operative oncology group (ECOG) performance status -1 and 1 patient had ECOG PS -2. B symptoms were seen in 3 out of 5 patients (60 %). According to IPI, 3 patients (60%) were in low intermediate risk and 2 patients (40%) had low risk score. 1 case was positive for BCL-6, 1 case was positive for CD10, 3 cases were positive for BCL-2, and 4 cases were positive for CD 20 . Patients were treated by various combinations of surgery, chemotherapy, and radiotherapy. Overall survival ranged from 6 months to 41 months with median OS of 23 months.Read Complete Article at ijSciences: V52016041011 AND DOI: http://dx.doi.org/10.18483/ijSci.1011