Ischemic stroke as a rare cause of seizures in a newborn – case report

Main Authors: Widłak, Karolina, Wójtowicz, Agnieszka, Ściślak, Robert, Drankowska, Justyna, Kos, Michał, Szuster, Aleksandra, Tarkowska, Agata, Szponar, Elżbieta, Furmaga-Jabłońska, Wanda
Format: Article
Terbitan: , 2019
Online Access: https://zenodo.org/record/3265753
Daftar Isi:
  • Widłak Karolina, Wójtowicz Agnieszka, Ściślak Robert, Drankowska Justyna, Kos Michał, Szuster Aleksandra, Tarkowska Agata, Szponar Elżbieta, Furmaga-Jabłońska Wanda. Ischemic stroke as a rare cause of seizures in a newborn – case report. Journal of Education, Health and Sport. 2019;9(7):76-84. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.3265753 http://ojs.ukw.edu.pl/index.php/johs/article/view/7100 https://pbn.nauka.gov.pl/sedno-webapp/works/917060 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Authors 2019; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 20.06.2019. Revised: 25.06.2019. Accepted: 02.07.2019. Ischemic stroke as a rare cause of seizures in a newborn – case report Karolina Widłak1,a, Agnieszka Wójtowicz1, Robert Ściślak1, Justyna Drankowska1, Michał Kos1, Aleksandra Szuster1, Agata Tarkowska2, Elżbieta Szponar2, Wanda Furmaga-Jabłońska2 1Students’ Scientific Group at the Department of Neonate and Infant Pathology 2Department of Neonate and Infant Pathology, Medical University of Lublin aE-mail address: karo.widlak@gmail.com Abstract Background: Identifying etiology of seizures is the primary clinical objective in the management of neonatal seizures (NS). About 85 % of NS cases occurr as a consequence of a specific, identifiable etiology. Causes of symptomatic NS can be broadly categorized as: hypoxic-ischemic encephalopathy, electrolyte or metabolic disturbances, CNS or systemic infections, developmental defects and acquired structural brain lesions, including hemorrhagic or ischemic stroke. Ischemic stroke is characterized as a sudden focal or generalized brain function disruption, whose symptoms tend to last longer than 24 hours (or cause death) and have no other reason but a vascular one. The reported annual incidence is estimated at one per 4000 live births for neonates. The aim of this case report is to present diagnostic difficulties in case of ischemic stroke in apparently healthy neonate. This case concerns a patient – a full-term male newborn, who was in a good condition in the first 3 days after birth. At the beginning of the 4th day of life 3 episodes of right-sided clonic seizures with right-sided nystagmus occurred and which was the reason for admitting the patient to the Department of Neonate and Infant Pathology. Shortly after arrival the seizures appeared again. Laboratory tests showed slightly lowered glucose level and elevated serum concentration of lactic acid. The ultrasound examination of the head revealed a small right-sided subependymal cyst. The patient’s condition was deteriorating, with recurring righ-sided clonic and tonic seizures accompanied by apnea and desaturation that required resuscitation efforts. Because of worsening state of the patient, CT scan was performed. The CT examination revealed a hypodensic area in the left parietal region and cerebral edema, which indicated a possible ischemic stroke. Conclusions: The absence of visible pathologies in the ultrasound examination of the head does not necessarily indicate a lack of CSN abnormalities. More precise imaging tests are needed to identify the cause of NS. Key words: Ischemic stroke