THE DESIGN AND SYNTHESIS OF NOVEL DERIVATIVES OF 3-HYDROXY-1, 2, 3, 4-TETRAHYDROQUINOXALINE-2-CARBOHYDRAZIDE DERIVATIVES
| Main Author: | Shripad Potadar * and Ramling Kotnal |
|---|---|
| Format: | Article |
| Terbitan: |
, 2019
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/3236677 |
Daftar Isi:
- ABSTRACT O-Phenylenediamine reacts with diethyl malonate to form ethyl 3-oxo-1,2,3,4- tetrahydroquinoxaline-2-carboxylate 2, which reacts with hydrazinehydrate to form ethyl 3-oxo-1,2,3,4- tetrahydroquinoxaline-2-carboxylate 3. Compound 3 on condensation with different aromatic aldehydes gives of 3-hydroxy-1, 2, 3, 4-tetrahydroquinoxaline-2-carbohydrazide. And The structures of these compounds are confirmed by 1H NMR and LC-MS data. KEYWORDS: Quinoxaline, Manolicacid, Hydrazinehydrate.