Severe ethylene glycol poisoning of 56 years old woman – case report
| Main Authors: | Klatka, Barbara, Terpiłowski, Michał, Janeczko, Dominika, Orzeł, Anna, Hołowczuk, Magdalena, Tchórz, Michał |
|---|---|
| Format: | Article |
| Terbitan: |
, 2019
|
| Online Access: |
https://zenodo.org/record/2619230 |
Daftar Isi:
- Klatka Barbara, Terpiłowski Michał, Janeczko Dominika, Orzeł Anna, Hołowczuk Magdalena, Tchórz Michał. Severe ethylene glycol poisoning of 56 years old woman – case report. Journal of Education, Health and Sport. 2019;9(4):55-62. eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.2619230 http://ojs.ukw.edu.pl/index.php/johs/article/view/6744 https://pbn.nauka.gov.pl/sedno-webapp/works/909332 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part b item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eissn 2391-8306 7 © The Authors 2019; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 01.03.2019. Revised: 15.03.2019. Accepted: 28.03.2019. Severe ethylene glycol poisoning of 56 years old woman – case report Barbara Klatka1, Michał Terpiłowski1, Dominika Janeczko1, Anna Orzeł1, Magdalena Hołowczuk1, Michał Tchórz2 Students’ Research Group at the Department of Toxicology, Medical University of Lublin Department of Toxicology, Medical University of Lublin Abstract Backgrounds: Ethylene glycol poisoning is one of the heaviest poisonings in the toxicological practice of. Ethylene glycol is quickly absorbed from the digestive tract. Its toxicity is the result of combining few different mechanisms. Metabolites of decomposition, especially glycolic acid, are responsible for appearance of metabolic acidosis. Precipitated crystals of calcium oxalate additionally impair the function of organs such as kidneys, central nervous system (CNS) and circulatory system. Worldwide, from 2013 to 2018 about 30% of ethylene glycol poisoning cases end in death. Case report: We present the case of 56 years old woman, who was admitted to Toxicology Department because of ethylene glycol poisoning. We could observe presence of metabolic acidosis, respiratory insufficiency and organ damage. The patient has been treated pharmacologically and has been given specific antidote. Due to the ethylene glycol intoxication, metabolic acidosis and increasing parameters of kidney failure the patient also underwent hemodialysis. Conclusions: In pathogenesis of ethylene glycol poisoning toxic metabolits are crucial. The diagnosis of ethylene glycol is often a very hard task. In the clinical aspect it is based on the interview, a set of syndromes and biochemical tests and targeted toxicological tests. This kind of poisoning occur the most often among patients addicted to alcohol. It may lead to multi- organ damage or even death. It is very important to react quickly and implement pharmacotherapy and hemodialysis. The other essential aspect is to improve the level of knowledge of students and doctors about symptoms, diagnostics and proper proceeding with a patient poisoned with ethylene glycol. According to statistics and knowing how often the alcohol poisoning happens it is necessary to have knowledge in this field, be fluent in management and choosing methods of treatment in such cases. Key words: poisoning; ethyleneglycol; toxicology