A computational protocol and software implementation (as a MATLAB application) for biomarker identification in infrared spectroscopy datasets
| Main Author: | sprotocols |
|---|---|
| Format: | Article Journal |
| Terbitan: |
, 2015
|
| Online Access: |
https://zenodo.org/record/15618 |
Daftar Isi:
- One attractive possibility of infrared (IR) spectroscopy is that it may be applied to investigate class (i.e., treatment, tissue type, etc)-specific alterations in the absorption signature. Such alterations can act as biomarkers of mechanism associated with pathways or effects. One may be interested in investigating such alterations from different standpoints including: (1) intensity; (2) statistical significance; and, (3) composite (multi-spectral-region) alterations. These three view-concepts were implemented computationally and named BM1, BM2 and BM3. They can be easily applied to datasets of classed IR spectra through a user-friendly MATLAB interface.