PREVALENCE OF ALZHEIMER'S DISEASE IN PATIENTS OF TYPE II DIABETES MELLITUS
| Main Author: | Dr. Muhammad Adnan Aslam, Dr. Moazzam Javid, Dr.Zahid Bashir |
|---|---|
| Format: | Article |
| Bahasa: | eng |
| Terbitan: |
, 2018
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/1492868 |
Daftar Isi:
- Type II Diabetes mellitus (DMT II) may increase Alzheimer's disease (AD) associated risk of dementia by various biological pathways, but the relationship between DM and AD development remains unclear. Objective: The aim of this study was to investigate the main risk factors for dementia and cognitive impairment in patients with Alzheimer's disease after Diabetes mellitus, and to differentiate the development of Alzheimer's disease risk in people with and without DM. Study Design:A Cohort Study. Place and Duration: In the Neurology outpatient department Ganga Ram hospital Lahore for one year period from July 2017 to June 2018. Methods: Among 410 participants,214 were diabetic and 196 were non-diabetic. A Mini-Mental State Examination (MMSE) was performed. Blood glucose levels were determined randomly at each visit; a complete examination of all participants was performed clinically. Results: In this study, we concluded that excessive weight loss due to diabetes duration, age and related conditions increase dementia and chi-square tests support the results. Diabetic patients with obesity were thought to have higher AD development possibilities and diabetic patients on borderline threshold also had a higher risk of developing AD. Conclusion: The study showed that one of the most important risk factors to increase the risk of AD is diabetes mellitus type II. However, obesity may cause pathological problems in participants with Alzheimer's disease. Dementia decreases with life style modifications. Key words: Dementia, Obesity, cognitive impairment, Alzheimer's disease (AD), diabetes mellitus type II(DMTII).