RehabMove 2018: THE IMPLEMENTATION OF VO2 KINETICS TO EVALUATE TRAINING EFFECTS IN CANCER PATIENTS

Main Authors: Vegter, R.J.K., Doornbos, A.J.H., Van Dijk, F.W., Dekker, R., Wempe, J.B., Hijmans, J.H.
Format: Proceeding
Bahasa: eng
Terbitan: , 2018
Online Access: https://zenodo.org/record/1483583
Daftar Isi:
  • PURPOSE: Oxygen uptake (V̇O2) kinetics can be used to measure exercise capacity. A constant work rate (CWR) test at moderate intensity measuring V̇O2 on-kinetics may be more suitable for a deconditioned patient population and a valuable source of information on training effects in addition to the regular exercise tests. The main goal of this study was to compare the sensitivity of V̇O2 on-kinetics during a rest-to-submaximal exercise transition to the regular variables measured in an incremental cardiopulmonary exercise test (CPET): ventilatory threshold (VT), V̇O2peak and peak work rate (WRpeak) to exercise induced changes, and to evaluate the usefulness of V̇O2 on-kinetics in determining an improved exercise capacity with respect to CPET in cancer patients. METHODS: Ten cancer patients (7 females) with a variety of cancer types aged between 39 and 64 years were enrolled in a 12-week rehabilitation program, in which they performed combined cycle-ergometer and strength training for two times a week. At initial and final evaluations, V̇O2 on-kinetics were measured breath-by-breath during a CWR test of moderate intensity, and V̇O2peak and VT were measured with a CPET. RESULTS: Comparisons between pre- and post-intervention showed large effect sizes for V̇O2peak (r = .59) and oxygen uptake at VT (r = .56). V̇O2 on-kinetics did not change after the training program. CONCLUSION: The current results suggest that V̇O2 on-kinetics is not more sensitive to exercise-induced adaptations compared to V̇O2peak and VT. However, V̇O2 on-kinetics did increase in eight of the ten subjects, and can serve as a source of information on training progress, especially when other information is lacking due to a non-maximal CPET or an unreliable VT.